Stenhousemuir striker Alex Williams may return to the starting after making his comeback from long-term injury as a substitute last week.Goalkeeper Chris McCluskey as well as Scott Dalziel, Simon Lynch and Ross Clark are missing while Willie Lyle is an injury doubt.
However, on-loan St Mirren duo Ally Love and Mark McLellan have been cleared to play by the Paisley club.
Threave will be without Mark Nicol and Shaun Milligan is doubtful.
Stenhousemuir manager John Coughlin said: "We are short of front men so hopefully we will have Alex available to get the goals that will see us through."
Threave manager Dave McVittie: "I believe that we have a chance as although Stenhousemuir are a Second Division side, they are in the bottom half of that division.
"They look stronger than they did three years ago when we beat them and we are stronger than when they beat us the following season.
"With it being the third meeting in four years you could say that we know each other really well."
Source: BBC Sport
Source: BBC Sport